This gene codes for a single-pass type I membrane protein that belongs to the integrin beta chain family and has a VWFA domain and four cysteine-rich repeats. Integrins are the primary receptors for cell adhesion to extracellular matrix proteins in metazoans, and they also play a role in some cell-cell adhesions, transmembrane connections to the cytoskeleton, and the activation of various intracellular signaling cascades in vertebrates. Integrin beta-8 is a 95-kDa glycosylated polypeptide that looks like other beta-chain integrins. In mature synapses in mouse and rat brains, it forms a heterodimer with the Alpha-V chain.

The report " Global Integrin Beta 8 Market, By Disease (Arteriovenous malformation and Arrhythmogenic right ventricular cardiomyopathy), By Application (Flow cytometry, CyTOF and Others), and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) – Market Trends, Analysis, and Forecast till 2030”

Key Highlights:

Corbus Pharmaceuticals (NSDQ:CRBP) has signed licensing agreements for two monoclonal antibodies (mAbs) it has called CRB-601 and CRB-602.The business purchased CRB-601, a high-potency anti-alpha V beta 8 (anti-avb8 mAb) antibody from the University of California, San Francisco. Both alpha V beta 6 and alpha V beta 8 are inhibited by the CRB-602 antibody. Panorama Research Inc. provided Corbus with the antibody (Sunnyvale, Calif.). The mAb, according to Corbus, has the potential to treat fibrotic disorders.
Analyst View:

Integrin beta 8 is gaining attention as a potential therapeutic target for a variety of diseases and cancers. Continuing clinical trials and studies on Integrin beta 8 as a potential cancer therapy option are expected to boost the Integrin beta 8 market over the projected period. A crucial element driving global market expansion is the increased focus on new research by government agencies and significant corporations. Due to a growth in the number of people suffering from various health problems, the global Integrin beta 8 market is increasing.

Browse 60 market data tables* and 35 figures* through 140 slides and in-depth TOC on “Global Integrin Beta 8 Market, By Disease (Arteriovenous malformation and Arrhythmogenic right ventricular cardiomyopathy), By Application (Flow cytometry, CyTOF and Others), and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Trends, Analysis, and Forecast till 2030”

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