Strategies for Pancreatic Rejuvenation in Diabetic Patients
Strategies for Pancreatic Rejuvenation in Diabetic Patients
The rejuvenation of damaged beta cells in the pancreas points towards the possible cure for diabetes. The basic strategy for this is as follows
Diabetic Fasting Diet
This is not like keeping a fast. This has 2 main features.
A. Substituting glucose-rich foods by fructose-rich foods in breakfast and lunch.
The rationale for this is that unlike glucose, fructose is a sugar that does not require insulin to enter the cells. Hence, the beta cells are not under pressure to produce more insulin and get adequate rest for rejuvenation. In such a scenario, though the blood sugar will rise after taking fructose-rich foods, it will also fall equally rapidly after another 1-2 hours as there is fructose uptake by body cells.
B. Staying on a low-carb diet from lunch to the breakfast of the following day
The rationale for this is that since we are low of carbs for 16 hours and load on the beta cells to produce insulin reduces and they get adequate rest to revitalize and rejuvenate.
2. Improving insulin sensitivity
Drugs like metformin and herbs like Ginseng (especially root extracts) reduce insulin resistance and thereby improve the efficacy of the already existing insulin in the body.
This reduces the pressure on the beta cells to produce more insulin and gives them rest to revitalize and rejuvenate.
3. Stem Cell Therapy
The latest trends in stem cell therapy done by using mesenchymal progenitor cells indicate that the fresh pancreatic tissue generation leads to improved in-vivo insulin production leading to a direct reduction of dependence on external insulin and reversal of pancreatic damage and diabetes.
4. Herbal Treatment in Diabetes
The pharmacological mechanisms of the herbs can be classified as (1) decreasing carbohydrate absorption, (2) improving insulin sensitivity, (3) increasing peripheral glucose uptake, (4) stimulating insulin secretion, (5) potentiating endogenous incretins, (6) exerting antioxidant effects and decreasing cell apoptosis, and (7) increasing the glycogenesis or inhibiting hepatic glycogenolysis (Source: National Institute of Health, US)
All of the above effects reduces the pressure on the beta cells to produce more insulin and gives them rest to revitalize and rejuvenate. Thankyou