Probably also affect the blood glucose metabolism through the improvement of insulin sensitivity and insulin production. In a Dutch prospective cohort study of 38 094 adults (20-70 years) had a higher intake of vitamin K (especially vitamin K2) associated with a significantly lower risk of type 2 diabetes during the follow-up period of more than 10 years. (16 ) Vitamin K1 reduced the risk of diabetes only with a high intake, while vitamin K2 there was a linear inverse association. It was also a higher intake of vitamin K2 was associated with lower concentration of hsCRP (high-sensitivity C-reactive protein, cognilift a marker for sub-acute inflammation) and a more favorable blood lipid profile. The average intake of vitamin K1 and K2 were respectively 200 and 31 mcg per day. (16) In a U.S. study resulted supplementation with a high dose of vitamin K1 (500 mcg / day for 36 months) in a less rapid progression of insulin resistance in older (non-diabetic) male; vitamin K1 supplementation did not have this effect at (non-diabetic) women (60-80 years old).

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