The latest market report published by Credence Research, Inc. “Global In-Vitro ADME Services Market - Growth, Share, Opportunities, Competitive Analysis, and Forecast, 2016 - 2023,” the Global In- Vitro ADME Services Market was valued at USD 2,316.5 Mn in 2015, and is expected to reach USD 3,859.1Mn by 2023, expanding at a CAGR of 7.6% from 2016 to 2023.

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Market Insights

ADME stands for absorption, distribution, metabolism, and elimination, which is a pharmacokinetic term, used to understand the drug metabolism in the body. The ADME properties of any particular drug help the developer to understand about the safety and efficacy of the drug which further required for regulatory approval. These basic processes help in understanding the performance of the drug in the human body or tissue and help in toxicity testing instead of the traditional use of animal testing. The conventional drug development process is time consuming and in addition there is always risk of the toxicity and efficacy testing in vivo environment failing at later stages in human body. Therefore, ADME toxicity testing at the initial stage of drug development is preferred to further save time, cost and drug approval process, which is a driving factor for the market

In- Vitro ADME Services are categorized by type as Solution Properties, Drug Absorption & Transport, Drug Metabolism and Drug-Drug interaction. Out of the segment, drug absorption and transport occupied the largest market share of In- Vitro ADME Services due to a rise in demand for the cost-efficient drug absorption detection services, and incessant development in the study of drug absorption methods in preclinical trials.

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Based on the type, the Global In-Vitro ADME Services Market is segmented as follows:

Solution Properties
Drug Absorption and Transport
Drug Metabolism
Drug-Drug Interaction

As of the current market scenario, Europe is the largest regional market for In- Vitro ADME Services, followed by North America and the Asia Pacific. The major factors driving the Europe In-Vitro ADME market are intensive research and development activities taking place in the region of the drug discovery and drug metabolism at the academic level. Since outsourcing bio-processing activities of pharmaceutical and biotechnology companies is taking place from developed markets to developing markets such as Asia- Pacific, Brazil. Thus emerging economies are a budding market for research and development due to cost-effectiveness and reduced timeline

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Market Competition Assessment:

Key players in the global In-Vitro ADME Services systems market are

Absorption Systems LP, Albany Molecular Research, Inc. (AMRI), Aptagen, LLC, BIOalternatives SA, Sigma-Aldrich Co. LLC/ MilliporeSigma, BioTeSys GmbH, Calvert Labs, XenoTech, LLC, Cyprotex PLC, Cyprotex PLC, Solvo Biotechnology, TNO, WuXiAppTec, Centrillion Technology Holdings Ltd, In Vitro ADMET Laboratories, LLC, Covance, Inc, Quintiles IMS Holdings, Inc, Optivia Biotechnology Inc., PharmaronBeijing Company Ltd., Quest Pharmaceutical Services Holdings LLC, Thermo Fisher Scientific Inc., Charles River Laboratories International, Inc., EurofinsCerep SA, A

dmescope, Agilux, Alliance Pharma, BD Biosciences, Frontage Laboratories, Microconstants, Inc

Key Market Movements:

Raising ethical concern regarding animal for toxicity testing, regulatory bodies and government initiative to shift from animal toxicity testing towards in vitro methods
With the advancement in R&D, In-vitro ADME is comprehensive and new technology platform in drug designing and screening which help in obtaining better efficacy and safety profile of the drug thus reducing the attrition rate over the decade

There is a need to create a database to monitor the toxicity effect and drug pathway through the in vitro or in silico method, this act as a major driver for the ADME in vitro market
Evolution of Pre-clinical ADME toxicity plays a significant role in drug discovery and development process, aiding the venture capitalist to take financial decision w.r.t scientific decision regarding a drug discovery firm

Market Segmentation

By Type

Solution Properties
Drug Absorption and Transport
Drug Metabolism
Drug-Drug Interaction

By Geography Segment

North America (the U.S., Rest of North America)
Europe (U.K., Germany, France, Rest of Europe)
Asia Pacific (China, Japan, India, Rest of Asia Pacific)
Rest of the World (the Middle East & Africa, Latin America)

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