21 May 2019 – Buy Tamoxifen proposes a large range of opportunities for those who are planning to order Tamoxifen online for personal needs. Tamoxifen is a non-steroidal anti-oestrogen agent, which also has weak estrogenic properties. Its action is based on the ability to block oestrogen receptors. Tamoxifen, as well as some of its metabolites, compete with Estradiol for binding sites to the cytoplasmic oestrogen receptors in the tissues of the breast, uterus, vagina, the anterior pituitary gland and tumours with a high content of oestrogen receptors.

 

Tamoxifen has large indications for use: Breast cancer (oestrogen dependent), ovulatory infertility, some types of male infertility. Side effects like Dyspepsia, dizziness, oedema, leukopenia, thrombocytopenia, hypercalcemia, keratopathy, retinopathy, dysmenorrhea, hot flashes, vulvar itching, reversible cystic swelling of the ovaries may appear.

 

For women receiving tamoxifen should undergo regular gynaecological examination. When a bloody discharge from the vagina or vaginal bleeding, the drug should be stopped. At patients with bone metastases, the concentration of calcium in the serum should be determined periodically during the initial period of treatment. In case of marked violations, tamoxifen should be temporarily stopped. If there are signs of venous thrombosis of the lower extremities (pain in the legs or their swelling), pulmonary embolism (shortness of breath), the drug should be stopped. Tamoxifen can cause ovulation, which increases the risk of pregnancy, and therefore, it is recommended to use a mechanical or non-hormonal contraceptive during tamoxifen treatment for women who are sexually active, and for about 3 months after treatment with tamoxifen. During the period of therapy, it is necessary to periodically monitor blood coagulation parameters, calcium content in the blood, blood picture (leukocytes, platelets), liver function indicators, blood pressure, to be examined by an ophthalmologist. In patients with hyperlipidaemia in the course of treatment it is necessary to control the concentration of cholesterol and TG in the serum. Influence on the ability to drive motor vehicles and work with mechanisms: during the period of treatment, it is necessary to refrain from engaging in potentially hazardous activities that require increased concentration of attention and psychomotor speed.

 

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